Percent strength and ratio strength explained

Percent weight-in-volume (% w/v) means grams per 100 mL. Ratio strength 1:x means 1 g in x mL.

Method

  1. % w/v → grams = (percent ÷ 100) × volume in mL.
  2. 1:x (w/v) → mg/mL = 1000 ÷ x.

Worked examples

Example 1

How many grams of dextrose are in 500 mL of a 5% w/v solution? Round to 3 decimal places.

Show solution
  1. % w/v means grams per 100 mL
  2. 5% = 5 g / 100 mL
  3. 5 g/100 mL × 500 mL = 25 g

Answer: 25 g

Example 2

How many mg of drug are in 50 mL of a solution labeled 1:200 (w/v)? Round to 2 decimal places.

Show solution
  1. 1:200 w/v means 1 g in 200 mL, so 1,000 mg / 200 mL = 5 mg/mL
  2. 5 mg/mL × 50 mL = 250 mg

Answer: 250 mg

Example 3

How many grams of calcium chloride are in 10 mL of a 10% w/v solution? Round to 3 decimal places.

Show solution
  1. % w/v means grams per 100 mL
  2. 10% = 10 g / 100 mL
  3. 10 g/100 mL × 10 mL = 1 g

Answer: 1 g

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